Sodium Hyaluronate

Sodium Hyaluronate

Sodium Hyaluronate


  • Derived from Hyaluronic Acid (HA), it's a natural substance in the body, crucial for skin health and moisture retention.
  • Restores moisture and reduces ageing signs like wrinkles, fine lines, and sagging skin, promoting a youthful appearance.
  • Strengthens the skin's barrier, protecting against environmental damage.
  • Supports joint health and mobility in ageing.
  • Studies suggest potential implications for cellular health and tissue rejuvenation.
  • Higher molecular weight HA reduced wrinkles at 8 weeks in a 12-week study; all groups showed improved skin after 12 weeks.
  • Daily oral intake of 200 mg hyaluronic acid for 28 days reduced wrinkle size and enhanced skin hydration and elasticity in women with mild-to-moderate skin ageing.

What is Sodium Hyaluronate?

Sodium Hyaluronate is derived from Hyaluronic Acid (HA) and is a natural substance found in the human body, especially in the skin, eyes, and connective tissues. It's a type of glycosaminoglycan, a crucial compound for skin health.

One of its primary functions is to retain moisture, keeping tissues well-hydrated and lubricated. HA can hold up to 1000 times its weight in water, making it an exceptional hydrating agent (R).

Sodium Hyaluronate Impact on Ageing

As we age, our skin's natural production of HA diminishes. External application or supplementation with Sodium Hyaluronate aids in restoring moisture, improving skin elasticity, and reducing signs of ageing (R).

By retaining moisture, HA helps diminish the appearance of wrinkles, fine lines, and sagging skin, promoting a more youthful appearance (R).

It strengthens the skin's natural barrier, protecting it from environmental aggressors and enhancing its resilience against damage (R).

Sodium Hyaluronate and Longevity and Ageing Studies

In the body, Sodium Hyaluronate acts as a cushioning agent in joints, reducing friction and supporting joint health, potentially aiding in mobility as people age (R).

Studies have explored the potential of Sodium Hyaluronate in promoting longevity. Although more research is needed, its impact on cellular health and tissue rejuvenation hints at broader implications for ageing-related issues (R).

A 12-week study indicated higher molecular weight HA reduced wrinkles after 8 weeks, while all groups had better skin after 12 weeks. Oral hyaluronic acid reduced wrinkles and enhanced skin (R).

Among women experiencing mild-to-moderate skin ageing, a daily oral intake of 200 mg hyaluronic acid for 28 days resulted in reduced wrinkle size and boosted skin hydration and elasticity (R).

Sodium Hyaluronate

The analysis results of wrinkle replicas were examined over time following the ingestion of hyaluronic acid or the placebo, with changes measured from the baseline. Image source: Clinical, cosmetic and investigational dermatology 

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Written By Natasha Jordan

BHSc Nutritional Medicine, International health - University Of Queensland

Diploma In Dermal Science - AACDS

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