Methylsulfonylmethane (MSM)

Methylsulfonylmethane (MSM)


  • MSM is an organic sulfur compound in plants, animals, and humans.
  • Recognised for its sulfur content, MSM is a popular dietary supplement aiding joint health, reducing inflammation, and boosting body antioxidants.
  • Studies hint at MSM's potential in combating aging effects.
  • Its antioxidant qualities help reduce oxidative stress associated with aging.
  • Preliminary research suggests MSM's antioxidants and anti-inflammatory properties positively affect longevity and well-being.

What is MSM?

MSM, short for Methylsulfonylmethane, is an organic sulfur compound found in plants, animals, and humans. 

Recognised for its sulfur content, MSM is often consumed as a dietary supplement to support joint health, reduce inflammation, and boost antioxidant levels (R, R).

MSM Impact on Aging

Studies suggest that MSM may play a role in combating the effects of aging (R). 

Its antioxidant properties contribute to reducing oxidative stress, which is linked to aging and age-related ailments. By neutralising free radicals and supporting cellular health, MSM holds the potential to mitigate the signs of aging and promote a healthier lifestyle (R).

MSM and Longevity in Aging Studies

Preliminary studies suggest that MSM's antioxidant and anti-inflammatory properties could positively influence various aging-related factors, potentially supporting longevity and overall well-being (R).

This study examined the effects of Methylsulfonylmethane (MSM) on skin aging. Results showed improved wrinkle severity, skin firmness, elasticity, and hydration (R). 

Methylsulfonylmethane (MSM)

Image Sourced: Int J Vitam Nutr Res. Facial lines and wrinkles were assessed visually, subjectively by the participants, and through image analysis using error bars to denote the standard error of the mean. A photographic example from a subject taking 1 g/day of the supplement showed visible softening in the crow's feet area, indicating the supplement's effectiveness in reducing these signs of aging.

Individuals diagnosed with knee osteoarthritis who used MSM for 12 weeks experienced enhancements in both pain levels and physical functionality (R).

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Written By Natasha Jordan

BHSc Nutritional Medicine, International health - University Of Queensland

Diploma In Dermal Science - AACDS

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