Does NMN and NR Need Refrigeration?

Does NMN and NR require refrigeration

Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR) are supplements gaining popularity for their potential anti-aging benefits. Given their rising popularity, a common question among users is whether NMN and NR need refrigeration to maintain their efficacy.

Stability and Storage

The stability of NMN and NR is influenced by factors such as temperature, light, and humidity. High temperatures and excessive humidity can degrade these compounds, reducing their potency. Exposure to direct sunlight or light can also affect their stability. Therefore, proper storage is essential to maintain the effectiveness of these supplements.

Refrigeration: Is it Necessary?

Most NMN and NR supplements come in powdered form, or as capsules, and at AgeMate, we recommend storing these products in a cool, dark place at a temperature no higher than 40°C. While refrigeration is not strictly necessary for short-term storage, it can be beneficial in extending the shelf life of both NMN and NR, especially in warmer climates or during hot summer months.


Keeping these supplements in the refrigerator (not the freezer) can help minimise the risk of degradation caused by heat and ensure that they maintain their potency for a longer period.

AgeMate Guidelines

It's important to follow the specific storage instructions provided by AgeMate. Some products may have been formulated in a way that makes them more stable at room temperature, while others might benefit more from refrigeration. Always check the label for storage recommendations.


While NMN and NR do not necessarily need to be refrigerated, doing so can help preserve their effectiveness, particularly in warmer environments. Proper storage, away from direct light and moisture, is key to ensuring you get the most out of your NMN and NR supplements. As with any dietary supplement, consult the product's labelling and, if in doubt, contact our team here, for the most accurate storage instructions.

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Written By Natasha Jordan

BHSc Nutritional Medicine, International health - University Of Queensland

Diploma In Dermal Science - AACDS

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