Do You Need to Take Resveratrol With NMN?

Do You Need to Take Resveratrol With NMN?

The quest for longevity and the dream of turning back the biological clock has led to a surge in the popularity of NMN (Nicotinamide Mononucleotide) and Resveratrol. But do these supplements need to be combined to unlock their full potential? 

This blog dives into the interplay between NMN and Resveratrol to help you decide whether combining them could benefit your health.

Understanding NMN and Resveratrol

NMN stands for Nicotinamide Mononucleotide, a molecule that plays a crucial role in cellular energy production and is a precursor to NAD+ (Nicotinamide Adenine Dinucleotide). 

As we age, our NAD+ levels decline, which is associated with various age-related health issues. Supplementing with NMN can potentially boost NAD+ levels and support cellular health, metabolism, and energy production (R).

Conversely, resveratrol is a natural compound in foods like grapes, red wine, and peanuts. Known for its antioxidant properties, Resveratrol has been studied for its potential anti-aging effects and its ability to activate sirtuins, proteins associated with longevity and cellular function (R).

The Synergy Between NMN and Resveratrol

The combination of NMN and Resveratrol has garnered attention for its potential synergistic effects. NMN's role in boosting NAD+ levels complements Resveratrol's activation of sirtuin proteins, as sirtuins require NAD+ to function effectively. 

This interplay suggests that taking NMN could enhance the effectiveness of Resveratrol, promoting better health and longevity outcomes.

Do You Need to Take Them Together?

While the potential benefits of combining NMN and Resveratrol are compelling, whether you "need" to take them together depends on your health goals and preferences. 

The most compelling study to date on the topic found that compared with NMN alone, NMN combined with resveratrol could increase the levels of NAD+ in the heart and muscle by about 1.6 times and 1.7 times (R).

Essentially, each supplement offers unique properties but can potentially complement each other when taken together. However, taking them together is optional. If you prefer to focus on specific health concerns or have different wellness goals, you might take one supplement over another.

Making the Right Choice for Your Health

Consider your health needs and goals before deciding whether to take NMN, Resveratrol, or both. Consult with a healthcare professional to understand how these supplements fit into your overall health regimen and whether combining them is the right strategy.

Remember, supplements should be part of a broader health and wellness strategy that includes a balanced diet, regular exercise, and adequate sleep. These lifestyle factors significantly affect your overall well-being and can enhance the effects of NMN and Resveratrol.


NMN and Resveratrol each offer promising benefits for aging and cellular health. While they can be taken separately, combining them may enhance their individual effects and synergistically support your health. However, the decision to take them together should be based on your health objectives and under the guidance of a healthcare professional.

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Written By Natasha Jordan

BHSc Nutritional Medicine, International health - University Of Queensland

Diploma In Dermal Science - AACDS

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