NMN

What is NMN?

What is NMN

Key Takeaways:

  1. NMN boosts NAD+ levels, supporting energy, healthy ageing, and vitality.
  2. NMN supplements improve metabolism, cognition, and reduce signs of ageing.
  3. Daily NMN intake promotes longevity and overall health.


NMN, or Nicotinamide Mononucleotide, is a molecule making some serious waves in the world of anti-ageing and longevity. NMN is a natural compound that helps your body produce NAD+ (Nicotinamide Adenine Dinucleotide), a coenzyme crucial for energy production and cellular repair.

 

But what exactly is NMN, and how can it benefit your health? Let’s take a deep dive into everything you need to know about this fascinating molecule.


What is Nicotinamide Mononucleotide (NMN)?


Nicotinamide Mononucleotide (NMN) is a naturally occurring compound found in small amounts in certain foods like broccoli, avocados, and edamame. It serves as a direct precursor to NAD+, a vital coenzyme that supports many essential functions in the body, including DNA repair, energy production, and cellular communication.


NAD+ levels decline with age. NAD+ levels can decline by up to 50% by middle age and drop as much as 80% by the time we reach old age. leading to reduced energy, slower metabolism, and other signs of ageing. Supplementing with NMN can help replenish these levels, promoting healthy ageing and longevity (R).

 

NMN molecular structure

 

How Does NMN Work?


NMN converts into NAD+ once inside your cells, acting as a fuel source for various metabolic processes. NAD+ is crucial for energy production, as it plays a key role in the electron transport chain within your mitochondria—the powerhouses of your cells. 


Additionally, NAD+ activates sirtuins, proteins known for their role in regulating cellular health and promoting longevity. By increasing NAD+ levels, NMN helps enhance these processes, making your cells more efficient and resilient (R).


NMN and NAD+: Understanding the Connection


NMN and NAD+ are closely related, but they serve different roles in the body. NMN is a precursor, meaning it’s converted into NAD+ once inside your cells. NAD+ is the active form that powers many vital processes, including DNA repair and cellular communication. Because NAD+ cannot be taken directly as a supplement (it’s too large to pass through cell membranes), taking NMN is one of the most effective way to raise NAD+ levels in the body (R).

 

NMN vs NR (Nicotinamide Riboside): Which is Better?


Both NMN and NR (Nicotinamide Riboside) are NAD+ precursors, but they work through different pathways in the body. 


NMN Pathway: NMN is directly converted into NAD+ by the enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT), allowing for rapid uptake into cells.


NR Pathway: NR is first converted into NMN by nicotinamide riboside kinase (NRK), which then converts into NAD+ via the same NMNAT enzyme, requiring additional conversion steps compared to NMN.


Research suggests NMN may have a stronger impact on muscle health and vascular function, while both NMN and NR can effectively boost NAD+ levels and support healthy ageing (R, R, R).

 

NMN supplement

 

What is NMN Used For?


NMN is primarily used as a supplement to support healthy ageing, energy production, and overall vitality. It’s particularly popular among those looking to enhance their quality of life as they age. Key benefits of NMN supplementation include:


  • Increased Energy Levels: By boosting NAD+ production, NMN helps your cells produce energy more efficiently, reducing fatigue and promoting sustained energy throughout the day (R).
  • Enhanced Cognitive Function: Research suggests that NMN can improve brain health, protect against cognitive decline, and support memory (R).
  • Better Metabolic Health: NMN supports healthy glucose metabolism, stabilising blood sugar levels and promoting weight management (R).
  • Improved Physical Performance: NMN can help improve endurance, muscle recovery, and overall exercise performance by ensuring your muscles have the energy they need (R).
  • Skin Health: NMN promotes cellular repair and regeneration, making it beneficial for maintaining youthful skin (R).

NMN and Longevity: How Does It Promote Healthy Ageing?


One of the most promising aspects of NMN is its potential to extend lifespan and promote healthy ageing. Research shows that maintaining high levels of NAD+ can protect against age-related conditions like metabolic disorders, neurodegenerative diseases, and even cardiovascular issues. By restoring NAD+ levels, NMN helps support mitochondrial function, reduce oxidative stress, and activate sirtuins—key factors that contribute to slowing the ageing process (R).


NMN and Metabolic Health: Supporting Your Body’s Energy Balance


By boosting NAD+ levels, NMN can enhance your body’s ability to metabolise glucose and fats, promoting better metabolic health. This can help stabilise blood sugar levels, reduce the risk of insulin resistance, and support healthy weight management—key factors in maintaining overall health as you age (R).


NMN and Cognitive Function: Supporting Brain Health


Research suggests that NMN may help protect against age-related cognitive decline by supporting neuronal health and enhancing energy production in brain cells. Studies have shown that NMN can improve memory and cognitive performance, making it a promising option for maintaining brain health as you age (R).


Is NMN Safe? Understanding Potential Side Effects


NMN has been shown to be safe in human studies. Most people tolerate NMN well, with few side effects reported (R). However, some individuals may experience mild symptoms like nausea, headache, or digestive upset. As with any supplement, it’s best to start with a lower dose and consult with a healthcare professional if you have any underlying health conditions.

 

NMN dosage guide

(References: 1, 2, 3)

 

How to Take NMN Supplements: Choosing the Right Form


NMN is available in various forms, including powders, capsules, and sublingual tablets. While all forms can effectively raise NAD+ levels, sublingual tablets and powders offer faster absorption since they enter the bloodstream directly.


Conclusion


NMN is a powerful supplement that can help support healthy ageing and longevity by boosting NAD+ levels, enhancing energy production, and protecting against age-related decline. Whether you’re looking to improve your energy levels, support cognitive function, or simply promote overall vitality, NMN could be the missing piece in your wellness routine.



Ready to experience the benefits of NMN for yourself? Try our Daily Longevity Blend—a premium formula designed to enhance NAD+ production, support cellular health, and promote longevity.

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Written By Natasha Jordan

BHSc Qualification in Nutritional Medicine, Postgraduate Degree in Public Health, Registered & Accredited through ANTA

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